姓名:孙端辰 性别:男
学位:博士 职称:教授
所在单位:山东大学数学学院
博士生导师 研究生导师
【教育经历】
2008.09—2012.06 山东师范大学,信息与计算科学,理学学士学位
2012.09—2017.06 中国科学院数学与系统科学研究院,运筹学与控制论,力学博士学位
【工作经历】
2017.07—2021.08 Oregon Health & Science University
2022.01—至今 山东大学数学学院,教授
【研究领域】
研究领域为运筹学、生物信息学,主要从事数学、机器学习与前沿生物医学问题的交叉研究,工作涉及生物信息学与大数据分析等领域。
【科研成果】
[1]Jiating Yu. Incorporating network diffusion and peak location information for better single-cell ATAC-seq data analysis. Briefings in Bioinformatics, 25, 2024.
[2]Yang, Jiaxin. Multi-objective Optimization-Based Approach for Detection of Breast Cancer Biomarkers. 14088 LNCS, 716-726, 2023.
[3]Sun, Chenxi. Detecting Autism Spectrum Disorder from Functional Magnetic Resonance Imaging Data with an Ensemble Machine Learning Method. 13-20, 2023.
[4]Zhang, Chunxiao. MOFNet: A Deep Learning Framework of Integrating Multi-omics Data for Breast Cancer Diagnosis. 14088 LNCS, 727-738, 2023.
[5]CDK9 inhibition induces epigenetic reprogramming revealing strategies to circumvent resistance in lymphoma. Mol Cancer, 22, 2023.
[6]Yu, Jiating. Network Refinement: Denoising complex networks for better community detection. PHYSICA A, 617, 2023.
[7]Wang, Chuanyuan. ActivePPI: quantifying protein-protein interaction network activity with Markov random fields. Bioinformatics (Oxford, England), 39, 2023.
[8]Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data. Nature Biotechnology, 2021.
[9]Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes. Nature Communications, 2021.
[10]BET bromodomain inhibition blocks an AR-Repressed, E2F1-Activated treatment-emergent neuroendocrine prostate cancer lineage plasticity program. Clinical Cancer Research, 2021.
[11]Discovering cooperative biomarkers for heterogeneous complex disease diagnoses. Briefings in Bioinformatics, 2019.
【科研项目】
1.(包干项目)生物信息学,2024/01/01,2026/12/31,
2.基于时空多组学数据的肿瘤时空特征算法开发,2022/12/31,2024/12/31,
3.(包干项目)生物信息计算与复杂疾病建模中的算法研究,2023/07/05,2025/12/31,
4.分子尺度多组学数据的数学表征与耦合集成,2022/12/01,2027/11/30,
5.(包干项目)单细胞导向的复杂疾病生物标志物识别新方法研究,2022/09/07,2025/12/31,
6.图理论和算法研究及其在生物信息学中的应用,国家自然科学基金,参与,2016-2021,
【联系方式】
通讯地址:山东大学中心校区知新楼B座913-1
邮箱:dcsun@sdu.edu.cn