姓名:孙端辰            性别:男
学位:博士             职称:教授
所在单位:山东大学数学学院
博士生导师             研究生导师
【教育经历】
2008.09—2012.06      山东师范大学,信息与计算科学,理学学士学位
2012.09—2017.06      中国科学院数学与系统科学研究院,运筹学与控制论,力学博士学位
【工作经历】
2017.07—2021.08      Oregon Health & Science University
2022.01—至今        山东大学数学学院,教授
【研究领域】
研究领域为运筹学、生物信息学,主要从事数学、机器学习与前沿生物医学问题的交叉研究,工作涉及生物信息学与大数据分析等领域。
【科研成果】
[1]Jiating Yu. Incorporating network diffusion and peak location information for better single-cell ATAC-seq data analysis.  Briefings in Bioinformatics,  25,  2024. 
[2]Yang, Jiaxin. Multi-objective Optimization-Based Approach for Detection of Breast Cancer Biomarkers.  14088 LNCS,  716-726, 2023. 
[3]Sun, Chenxi. Detecting Autism Spectrum Disorder from Functional Magnetic Resonance Imaging Data with an Ensemble Machine Learning Method.  13-20, 2023. 
[4]Zhang, Chunxiao. MOFNet: A Deep Learning Framework of Integrating Multi-omics Data for Breast Cancer Diagnosis.  14088 LNCS,  727-738, 2023. 
[5]CDK9 inhibition induces epigenetic reprogramming revealing strategies to circumvent resistance in lymphoma.  Mol Cancer,  22,  2023. 
[6]Yu, Jiating. Network Refinement: Denoising complex networks for better community detection.  PHYSICA A,  617,  2023. 
[7]Wang, Chuanyuan. ActivePPI: quantifying protein-protein interaction network activity with Markov random fields.  Bioinformatics (Oxford, England),  39,  2023. 
[8]Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data.  Nature Biotechnology,  2021. 
[9]Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes.  Nature Communications,  2021. 
[10]BET bromodomain inhibition blocks an AR-Repressed, E2F1-Activated treatment-emergent neuroendocrine prostate cancer lineage plasticity program.  Clinical Cancer Research,  2021. 
[11]Discovering cooperative biomarkers for heterogeneous complex disease diagnoses.  Briefings in Bioinformatics,  2019. 
【科研项目】
1.(包干项目)生物信息学,2024/01/01,2026/12/31,
2.基于时空多组学数据的肿瘤时空特征算法开发,2022/12/31,2024/12/31,
3.(包干项目)生物信息计算与复杂疾病建模中的算法研究,2023/07/05,2025/12/31,
4.分子尺度多组学数据的数学表征与耦合集成,2022/12/01,2027/11/30,
5.(包干项目)单细胞导向的复杂疾病生物标志物识别新方法研究,2022/09/07,2025/12/31,
6.图理论和算法研究及其在生物信息学中的应用,国家自然科学基金,参与,2016-2021,
【联系方式】
通讯地址:山东大学中心校区知新楼B座913-1
邮箱:dcsun@sdu.edu.cn